Human HER3 / ErbB3 Protein (ECD, His Tag) 10201-H08H from Sino Biological, Inc. | Biocompare.com

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Human HER3 / ErbB3 Protein (ECD, His Tag)

Human HER3 / ErbB3 Protein (ECD, His Tag)

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Sino Biological, Inc. for
Human HER3 / ErbB3 Protein (ECD, His Tag)

Description

A DNA sequence encoding the extracellular domain (Met 1-Thr 643) of human ErbB3 (NP_001973.2) precursor was expressed, with a C-terminal polyhistidine tag

Product Specs
ItemHuman HER3 / ErbB3 Protein (ECD, His Tag)
CompanySino Biological, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog Number10201-H08H
Quantity500µg
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human ErbB3 protein consists of 635 amino acids after the removal of signal peptide and has a calculated molecular mass of 70.2 kDa. As a result of glycosylation, the recombinant ErbB3 migrates as an approximately 100-110 kDa band in SDS-PAGE under reducing conditions
SpeciesHuman
ProteinERBB3
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameerb-b2 receptor tyrosine kinase 3
NCBI Gene AliasesErbB-3, FERLK, HER3, LCCS2, MDA-BF-1, VSCN1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
Activity1. Measured by its binding ability in a functional ELISA. 2. Immobilized human ErbB3 at 2 µg/mL (100 µl/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.43 µg/mL
FormatLyophilized from sterile PBS, pH 7.4

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Sino Biological, Inc.

Sino Biological, Inc.

1400 Liberty Ridge Drive

Suite 101

Wayne, PA 19087

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: http://www.sinobiological.com/

(1) Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft ModelPharmaceuticsJune 13, 2020Leitao CD, Rinne SS, Altai M, Vorontsova O, Dunås F, Jonasson P, Tolmachev V, Löfblom J, Ståhl S, Orlova A.

(2) Optimization of HER3 expression imaging using affibody molecules: Influence of chelator for labeling with indium-111Scientific reportsJanuary 24, 2019Rinne SS, Leitao CD, Mitran B, Bass TZ, Andersson KG, Tolmachev V, Ståhl S, Löfblom J, Orlova A.

(3) Site-Specific Photoconjugation of Beta-Lactamase Fragments to Monoclonal Antibodies Enables Sensitive Analyte Detection via Split-Enzyme ComplementationBiotechnology journalJuly 1, 2018Yu F, Alesand V, Nygren PÅ.

(4) Development and characterization of small bispecific albumin-binding domains with high affinity for ErbB3Cellular and molecular life sciences : CMLSOctober 1, 2013Nilvebrant J, Astrand M, Löfblom J, Hober S.

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